Wednesday, September 24, 2014

Research Reveals How Sugar CAUSES Cancer

New Research Shows That Sugar Causes Cancer 

The role of sugar in the formation, growth and metastasis of cancer cells is a topic that has often divided the scientific community. While the Canadian Cancer Society explicitly states that eating sugar does not make cancer cells grow faster, other trustworthy sources disagree and claim just the opposite. A recent research published in the Journal of Clinical Investigation now provides experimental evidence that suggest the anti-sugar camp was right all along.

The so called Warburg effect describes how most cancer cells produce energy through aerobic glycolysis, which means that they metabolize sugar. Normal tissue has very low glycolitic rates; about 200 times lower than the fast growing cancer cells. The process was named after Otto Warburg, who was the first to hypothesize that this change in metabolism is the fundamental cause of cancer. Even if Warburg’s theory received a lot of publicity when it was published and even won him a Nobel Prize, it was later sidetracked. Most of the current literature views the shift to aerobic glycolysis as a result of cancer, rather than its cause. But new research brings the Warburg effect back to the center of cancer research.

Yasuhito Onodera and his colleagues confirmed that increased sugar intake promotes cancer development or oncogenesis. The research team showed that increased glycolytic activation caused over expression of glucose transporter type 3 (GLUT3) in non-malignant human breast cells. This resulted in the activation of known oncogenic signaling pathways. When malignant cells received less glucose, this promoted the formation of organized structures that didn’t grow as rapidly, and suppressed oncogenic pathways. In other words, if sugar was less available, the cancer cells reversed towards their pre-cancer structure. Researchers used a 3D culture model and showed that glucose uptake levels determined whether breast cancer cells formed colonies with malignant or non-malignant behavior.

For the rest of the story: http://www.healthyandnaturalworld.com/new-research-shows-sugar-causes-cancer/

No comments:

Post a Comment