A world without heart disease seems impossible. But researchers at Johns Hopkins just got one step closer.
Scientists at Johns Hopkins University may be one step closer to eradicating debilitating heart diseases in humans, particularly those caused by excessive buildup of cholesterol.
A new study published in the journal Circulation shows that a synthesized drug reduces, and may even eradicate, the effects of high-fat and high-cholesterol diets. And though the drug is prosperous for the heart and brain most specifically, the entire body may benefit from this development.
“It’s the entire cardiovascular system that’s affected,” Ekaterina Pesheva, a representative for Johns Hopkins, told The Daily Beast. “The reason we’re worried about the heart and the brain is because those are the centers that end up being the most debilitating to human life when affected by fatty buildups.”
The study shows that the new drug under examination, known now as D-PDMP, changes the way fat metabolism works, and eliminates the risk of heart attack and heart disease. The drug halts the development of atherosclerosis, a word referring to the hardening of the arteries. Atherosclerosis is based on a buildup of fat and cholesterol in blood vessels, and happens to be the main cause of heart attacks in humans. Most notably, atherosclerosis is the No. 1 cause of death in humans (perhaps a little-known fact in a world rampant with famine, war, and crime).
Atherosclerotic heart disease is the most common type of heart disease, which develops when fat builds inside the blood vessels over time, rendering them stiff, narrowed, and hardened. This, in turn, reduces blood flow to the heart and brain.
Other kinds of heart disease include structural heart disease—people born with malformations of their heart, which is rare, and heart failure (mostly a result of poorly functioning heart muscle, which can be due to a number of causes, including atherosclerosis. It can also be caused by other conditions such as viral infections of the heart) will also benefit from this development.
For the rest of the story: http://www.thedailybeast.com/articles/2014/04/25/scientists-at-johns-hopkins-come-closer-to-eliminating-heart-disease.html